What question or challenge were you setting out to address when you started this work?

Question: What question or challenge were you setting out to address when you started this work?
- Keywords:
  challenge,
  work
Asked by anon-196637 to Sebastian, Paddy, Lee, Jennifer, Fiona, Eleanor on 8 Mar 2019.
- Jennifer Harris answered on 8 Mar 2019:
  
  I wanted to know how and why the immune system is switched off in early stages of skin cancer.
- Sebastian Cosgrove answered on 8 Mar 2019:
  
  In my work I want to try and improve the chemical processes we use to make important molecules, such as drugs. So we set out to try and see if we could make a certain set of chemicals, called amines, using a new method that had never been done before.
- Fiona Scott answered on 8 Mar 2019:
  
  The questions my PhD thesis is asking is: “Can you make drugs for a poorly understood enzyme called PRK2?” and “Does using these drugs help us understand PRK2’s role in cancer?”. The answer to that first question is currently yes!

Question: What question or challenge were you setting out to address when you started this work?